CPK-MB
A cardiac enzyme test that detects heart muscle damage, commonly used when a heart attack is suspected.
Test Information
Reports In
Same day (5-6 hours)
Parameters
1
Requisites
Blood Sample
Sample Type
Blood
Measures
Creatine kinase-MB (CK-MB) enzyme level—the heart-specific fraction of creatine kinase that rises when heart muscle cells are damaged.
Identifies
Acute myocardial infarction (heart attack), heart muscle damage from reduced blood flow, and helps distinguish cardiac injury from skeletal muscle injury.
What is the CPK-MB Test?
CPK-MB (Creatine Phosphokinase-MB) is an enzyme found primarily in heart muscle. When heart muscle is damaged (as in a heart attack), CPK-MB leaks into the bloodstream. This test helps diagnose heart attacks and distinguish them from other causes of chest pain. It's one of the key cardiac markers used in emergency settings.
Why Should You Take This Test?
Heart disease is the leading cause of death in India. When someone presents with chest pain, CPK-MB (along with Troponin) helps confirm or rule out a heart attack. Early diagnosis enables prompt treatment—critical for saving heart muscle and lives.
Who Should Get Tested?
Chest Pain
To rule in or rule out a heart attack.
Suspected Heart Attack
CPK-MB rises 4-6 hours after cardiac injury.
Post-Cardiac Procedure
Monitoring for heart muscle damage after procedures.
Heart Disease Patients
Tracking heart muscle health.
Warning Signs — When Should You Get This Test?
Common Conditions Detected
Frequently Booked Together
Tests commonly ordered alongside CPK-MB for a complete picture
Troponin I
More specific cardiac marker — ordered alongside CPK-MB
ECG
Electrical activity of the heart during chest pain
NT-proBNP
Assesses heart failure risk
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